The versatility and flexibility of the Fitzpatrick FitzMill has made it the primary size reduction technology for APIs. Utilized universally throughout the pharmaceutical industry, it is used for milling a range of other “difficult –to-mill” pharmaceutical powders.
The Fitzpatrick FitzMill and Its Role In Sizing Active Pharmaceutical Ingredients Read More »
The analysis of particle size distribution is an important parameter for FDA process validation. The narrower the particle size distribution range, the more product there is being produced that meets the exact particle size specifications for formulation and bioavailability. Both Conical Milling and Hammer Milling are successfully used to regulate particle size and shape, and achieve consistent tight particle size distributions, leading to quality products and efficient production systems. The choice of whether to use Conical Milling or Hammer Milling will be decided by several factors including an evaluation of the type of product that is needed to be processed, and the results required.
The Importance of Particle Size Distribution in Pharmaceuticals Read More »
Coperion K-Tron example flow diagrams for various nutraceutical and pharmaceutical applications including direct blender loading with in-line air swept sieve.
System Flow Diagrams – Pharmaceutical and Nutraceutical Systems Read More »
Matcon are powder handling experts who were established 40 years ago. Our materials handling solutions include automated systems for formulation, transfer, and discharging of the complex ingredients used in Lithium-ion battery production and recycling, providing safe, efficient handling options for all powders.
IBC Handling and Tumble Blending for Lithium Battery Industry Read More »
This customer had existing equipment to deliver salt into their auger filler. The salt comes in bulk bags as a solidified block and is conditioned offline in a warehouse using a hydraulic bag conditioner. The primary issue for this application was to maintain a consistent, uniform material supply into the auger filler for it to operate properly. The customers’ existing discharge station features a small agitator that would break up material into irregular sized chunks that would not provide a uniform material supply into the auger filler. This results in off-spec filled packages that would need to be reprocessed.
Understanding the application requirements, NBE conducted a test with the customer at our Innovation Center and Application Workshop. We used a bulk bag discharger with integral lump breaker (with screen), along with a screw conveyor, to unload the bag and process it into a consistent supply of material. The salt was broken down back to nearly original particle size. The customer was thrilled with the outcome.
Bulk Bag Discharger and Flexible Screw Conveyor for Table Salt Read More »
The customer needed a replacement system to combine and dissolve sodium chloride with water into a brine to feed their downstream process. Their existing system was labor intensive, unreliable, and hard to keep clean. Looking to make enhancements in those areas, along with improved safety and accuracy, NBE provided a bulk bag unloader equipped with E2, dust collection, crumbler, flexible screw conveyor, and safety caging. The sodium chloride is fed into a fiberglass reinforced plastic (FRP) tank to be combined with water, utilizing a Brawn mixer to agitate the contents along with a high-shear inline mixer to shear the sodium chloride particles and quickly dissolve them. High accuracy of additions is achieved with load cells on the dry addition and a magnetic flowmeter on the water side. Conductivity instrumentation is installed in the mixing tank to verify correct solution concentrations. Sodium chloride solutions are very corrosive, so special materials such as Hastelloy, AL6XN, FRP, and CPVC were chosen for various components. NBE provided a full control package including PLC and HMI set up for automatic operation.
Liquid Slurry System for Water and Sodium Chloride Read More »
This packaging system is designed to fill lined 55-gallon open-head steel drums with viscous resins and hardeners in a continuous fashion semi-automatically. Two systems were supplied to optimize through put and isolate product mixes. The equipment features a removable supply manifold utilized to transfer product to the filling zone. Two profile cut valves with infinite positioners control the flow of product to the direct fill nozzles based on feedback from the net weight scales. The F-Style design includes two infeed conveyors, two net weight filling stations, two turntables, and a common accumulation conveyor. The accumulation conveyor includes a continuous inkjet printer for applying date, lot, and weight information, a heated vacuum sealer, and a manual lidding station. With a roller height of just 6.5” the low-profile conveyors were designed with ergonomics in mind. The polycarbonate enclosure serves to improve operator safety while also maintaining a low moisture environment within the filling zone through utilization of dry air nozzles throughout.
Semi-Automatic Drum Filling System for Resins and Hardeners Read More »
A large, international manufacturer of dry cell batteries approached Quadro to help them with the manufacture of their battery products. The battery employed several powder mixtures of Teflon, Carbon Black powder and 1/8″ pieces of Graphite. The customer was getting 30% – 40% of the product below 60 mesh USS, by running a single-pass through a Hammermill and two passes through the Comil®. Heat generation in the Hammermill caused blinding of the screen which slowed down production of the batteries. The customer wanted to eliminate the Hammermill stage. The required capacity rate was 13 lbs/hr.
Delumping and Dispersing Battery Powders Read More »
Whether feeding continuously or via batch the accuracy of addition is critical to the end quality and desired functionality of battery masses. While this is greatly impacted by the bulk materials themselves and the conditions, using the right tools to identify the best equipment will lead to the best possible system design. For handling of difficult materials, material tests are essential for determining optimal equipment configurations for both feeders and pneumatic conveying. With Coperion K-Tron’s wealth of experience, lab data, and technical expertise we can test and design systems for the most challenging of materials in any application, especially those for the battery industry.
Feeding and Conveying in the Production of Battery Masses Read More »
With the growing popularity of the single serve coffee pod comes the need for manufacturers to insure proper seal integrity. Teledyne TapTone has proven patented technology that can inspect one hundred percent (100%) of the container pods before the packages are shipped and the leaks are detected by the consumer. The size and shape of most coffee pods make them ideally suited for a T550 C-LP system outfitted with a TDLC sensor to yield the most sensitive and accurate method of leak detection.
Seal and Leak Detection of Single Use Coffee Pods Read More »